Cardiovascular effects of cholinergic agents microinjected into the nucleus tractus solitarii of the rat
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منابع مشابه
Mechanism of cardiovascular effects of nociceptin microinjected into the nucleus tractus solitarius of the rat.
Microinjections (100 nl) of 0.15, 0.31, 0.62, and 1.25 mmol/l of nociceptin into the medial nucleus tractus solitarius (mNTS) elicited decreases in mean arterial pressure (11 +/- 1.8, 20 +/- 2.1, 21.5 +/- 3.1, and 15.5 +/- 1.9 mmHg, respectively) and heart rate (14 +/- 2.7, 29 +/- 5.5, 39 +/- 5.2, and 17.5 +/- 3.1 beats/min, respectively). Because maximal responses were elicited by microinjecti...
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To determine whether the central vasopressinergic system at the level of nucleus tractus solitarii (NTS) modulates the reflex control of heart rate, we employed a new method for microinjection into the brainstem of conscious, freely moving rats. Baroreceptor reflex function was assessed during pressure changes induced by intravenous administration of phenylephrine (0.25-8 micrograms/kg) and sod...
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Corresponding author: Hidefumi WAKI, Ph.D. Department of Physiology, Wakayama Medical University School of Medicine, 811-1 Kimiidera, Wakayama 641-8509, JAPAN Phone: +81-73-441-0623 (Office of Department) Fax +81-73-441-0623 (Office of Department) E-mail: [email protected] Short title: IL-6 in NTS attenuates baroreflex Articles in PresS. Am J Physiol Regul Integr Comp Physiol (November ...
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15 صفحه اولCardiovascular responses to microinjection of ATP into the nucleus tractus solitarii of awake rats.
Microinjection of increasing doses of ATP (0.31, 0.62, 1.25, and 2.5 nmol/50 nl) into the nucleus tractus solitarii (NTS) produced a dose-dependent pressor response. Prazosin abolished the pressor response and produced no change in the bradycardic response to ATP. Microinjection of pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid (0.25 nmol/50 nl), a nonselective P2 receptor antagonist int...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1985
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)63771-6